Journal of Family Medicine and Primary Care

ORIGINAL ARTICLE
Year
: 2019  |  Volume : 8  |  Issue : 2  |  Page : 634--639

Promising pain-relieving activity of an ancient Persian remedy (mixture of white Lily in sesame oil) in patients with chronic low back pain


Saeed Rasoulinezhad1, Nafiseh Hosseini Yekta1, Ehsan Fallah2 
1 Department of Persian Medicine, Faculty of Medicine, AJA University of Medical Sciences, Tehran, Iran
2 Department of Orthopedic and Trauma Surgery, AJA University of Medical Sciences, Tehran, Iran

Correspondence Address:
Dr. Nafiseh Hosseini Yekta
Department of Persian Medicine, Faculty of Medicine, AJA University of Medical Sciences, Tehran
Iran

Background and Objectives: Chronic low back pain (CLBP) is one the frequent musculoskeletal issues among adults mostly without a specific etiology. In this study, we investigated a traditional Persian remedy for back pain which is based on topical application of a mixture of sesame oil (SO) and white lily (LSM). Materials and Methods: The chemical profile, phenol content, and antioxidant activity of the herbal samples were determined using GC-MS, total phenol content (TPC) assay, and DPPH assay, respectively. Clinical efficacy of the herbal samples by a double-blind placebo was examined. Results: TPC of SO and LSM was 45 ± 5.7 and 68.3 ± 11.2 mg GAE/g oil mixture, respectively. The SO could inhibit 59.7% of free radicals, whereas LSM showed a radical inhibition rate of 74.7% in DPPH assay. LSM could reduce the pain feeling and obtained the lowest pain scores (Oswestry disability index and numeric rating scale) in weeks 4 and 8 of therapy in comparison to other treatment groups (diclofenac gel and SO) and placebo control (Vaseline). Conclusions: The results implicate the LSM as a novel therapeutic alternative for the therapy of the CLBP.


How to cite this article:
Rasoulinezhad S, Yekta NH, Fallah E. Promising pain-relieving activity of an ancient Persian remedy (mixture of white Lily in sesame oil) in patients with chronic low back pain.J Family Med Prim Care 2019;8:634-639


How to cite this URL:
Rasoulinezhad S, Yekta NH, Fallah E. Promising pain-relieving activity of an ancient Persian remedy (mixture of white Lily in sesame oil) in patients with chronic low back pain. J Family Med Prim Care [serial online] 2019 [cited 2021 Jun 14 ];8:634-639
Available from: https://www.jfmpc.com/article.asp?issn=2249-4863;year=2019;volume=8;issue=2;spage=634;epage=639;aulast=Rasoulinezhad;type=0