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 Table of Contents 
ORIGINAL ARTICLE
Year : 2021  |  Volume : 10  |  Issue : 4  |  Page : 1687-1693  

The utility of Problem Areas in Diabetes (PAID) scale amongst patients with Type 2 diabetes (T2DM): An experience from a teaching hospital in southern India


1 Aberdeen Royal Infirmary, Foresterhill, Aberdeen, UK
2 Department of Endocrinology, Diabetes and Metabolism, Christian Medical College, Vellore, Tamil Nadu, India
3 Medical Statistics Team, Division of Applied Health Sciences, University of Aberdeen, Foresterhill, Aberdeen, UK
4 Department of Biostatistics, Christian Medical College, Vellore, Tamil Nadu, India
5 JJR Macleod Centre for Diabetes, Endocrinology and Metabolism, David Anderson Building, Aberdeen Royal Infirmary, Foresterhill, Aberdeen, UK

Date of Submission15-Sep-2020
Date of Decision24-Dec-2020
Date of Acceptance13-Feb-2021
Date of Web Publication29-Apr-2021

Correspondence Address:
Dr. Hesarghatta S Asha
Department of Endocrinology, Diabetes and Metabolism, Christian Medical College, Vellore - 632 004, Tamil Nadu
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jfmpc.jfmpc_1891_20

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  Abstract 

Objectives: The purpose of this study was to establish the prevalence of diabetes-specific psychological distress (DSPD) among patients with type 2 diabetes mellitus (T2DM) using the “Problem areas in diabetes” (PAID) scale at a teaching hospital in southern India. Other objectives included observing the relationship between socio-demographic factors and DSPD and, finally exploring the level of acceptance of the PAID scale by Asian–Indian patients. Methods: The patients with T2DM aged >18 years attending the diabetes outpatient clinic were recruited. They completed two sets of questionnaires; PAID and a satisfactory questionnaire, which included socio-demographic characteristics and questions relating to the acceptance of PAID. Statistical analysis was performed using Stata 13.1 and Excel. Results: A total of 253 questionnaires were completed, including 157 (62.1%) male and 96 (37.9%) female patients. The prevalence of DSPD was 32.8% (83/253). Younger age (OR 3.65, 95% CI 1.36–9.80) and presence of retinopathy (OR 2.60, 95% CI 1.12–6.04) were significantly associated with DSPD. However, it was observed that one-third of the patients had an elevated level of distress regardless of socio-demographic or clinical factors. PAID was well accepted by the participants and 84.6% (214/253) were pleased to complete it again. Conclusion: About one-third of the patients with T2DM had DSPD. Psychological distress was higher in the younger age group and those with retinopathy. PAID is an easy, well-accepted questionnaire and would serve as a useful tool to screen for DSPD.

Keywords: India, Problem Areas In Diabetes, psychological distress, type 2 Diabetes mellitus


How to cite this article:
Thomas L, Asha HS, Amalraj RE, Prakash R, Abraham P, Thomas N. The utility of Problem Areas in Diabetes (PAID) scale amongst patients with Type 2 diabetes (T2DM): An experience from a teaching hospital in southern India. J Family Med Prim Care 2021;10:1687-93

How to cite this URL:
Thomas L, Asha HS, Amalraj RE, Prakash R, Abraham P, Thomas N. The utility of Problem Areas in Diabetes (PAID) scale amongst patients with Type 2 diabetes (T2DM): An experience from a teaching hospital in southern India. J Family Med Prim Care [serial online] 2021 [cited 2021 May 18];10:1687-93. Available from: https://www.jfmpc.com/text.asp?2021/10/4/1687/314905




  Introduction Top


Diabetes mellitus (DM) affects millions of people worldwide; however, it is more pronounced in the Indian subcontinent.[1] Studies report that between 2000 and 2030, the greatest absolute increase in the number of people with diabetes will be in India.[2] Type 2 diabetes mellitus (T2DM) accounts for 90% of all diabetes and India has seen a substantial rise in its prevalence along with a shift in diagnosis of T2DM in the younger population.[1],[3–5] This shift in the age of diagnosis is of concern as it may have adverse consequences on the nation's health and economy.

The main focus of diabetes management is on lifestyle changes and pharmacotherapy. Optimal self-management requires a significant amount of time and effort. As is the case with all chronic diseases, psychological distress can have a detrimental impact on diabetes self-management.[6],[7] The burden of self-care and pharmacological therapy, especially with insulin injections may overwhelm or burn-out patients.[8],[9] Adjustment to the disease is often associated with various negative emotional responses including anger, guilt, frustration, denial and loneliness.[10] The impact of glycaemic control and its effect on long-term complications may also aggravate feelings of fear and depression.[8] These responses are classified as 'Diabetes-specific Psychological Distress (DSPD)'. It is a separate entity from general emotional distress and was developed to specifically assess psychological distress related to diabetes.[9] The estimated prevalence of psychological distress in diabetes ranges from 18 to 52%.[9] With an increasing prevalence of T2DM at a younger age in India, it seems imperative to identify and manage psychological distress related to diabetes effectively.[1]

Quality of life (QoL) is assessed using self-reported questionnaires.[11] Problem areas in diabetes (PAID) is a well-validated, easy-to-administer, 20-item scale that measures DSPD.[12],[13] PAID uses a five-point Likert scale to assess the response to each item. The total score ranges from 0 to 100, achieved by summing 0–4 responses to 20 PAID items and multiplying the sum by 1.25.[14] A score of ≥40 denotes elevated levels of distress.[12–14] Psychometric reports to date on the PAID scale, have shown it to have a consistently high internal reliability (Cronbach's alpha = 0.95) and a sound two-month test–retest reliability (r = 0.83) in a group of patients.[14] It has also been demonstrated to be strongly associated with general emotional distress, depression, diabetes self-care behaviours, diabetes coping, and health beliefs; and to be a statistically significant predictor of glycaemic control in a study that tracked HbA1C for a diabetes population for one year.[8],[12],[14],[15]A large proportion of patients with T2DM are managed by primary care physicians. Assessment of DSPD using the PAID scale aids primary care providers to identify the barriers for diabetes self-management, and would guide treatment directed at overcoming the barriers, which in turn would result in better long-term diabetes control and reduction of its chronic complications.

The main purpose of this study was to establish the prevalence of DSPD among type 2 diabetes outpatients at a southern Indian teaching hospital, using the PAID questionnaire. The secondary objectives were to ascertain the relationship between socio-demographic factors and DSPD, and finally to explore the level of acceptance of the PAID scale by Indian subjects with diabetes.


  Materials and Methods Top


Study setting and subjects

This cross-sectional single-centre study was conducted at the Christian Medical College in Vellore, Tamil Nadu, India, from 7 January to 11 February 2015. The patients with T2DM, aged more than 18 years, attending the diabetes outpatient clinic at the Department of Endocrinology were eligible. Patients with other types of diabetes and those with a previous diagnosis of a psychiatric disorder were excluded.

Study design and data collection

Eligible participants were approached by the principal investigator whilst waiting at the diabetes outpatient clinic. Details of the study were explained verbally and a study information leaflet was given. Signed informed consent was obtained from all interested participants prior to administration of the PAID questionnaire in Tamil/English. They were also asked to complete a satisfactory and clinical indicators questionnaire which included socio-demographic characteristics (age, gender, place of residence, education, marital status, employment status, height and weight), information pertaining to their diabetes (duration of diabetes, associated medical problems, diabetes medications and adherence to medications) and complications (self-reported diabetic retinopathy, neuropathy, nephropathy, peripheral vascular disease [PVD], coronary artery disease [CAD] and foot problems). History of smoking and alcohol consumption were also recorded. The PAID scale was translated to Tamil by local bi-lingual experts, and independently back-translated to check for accuracy. It needed about 15 minutes to complete the two sets of questionnaires. Approval was obtained from the Institutional Review Board (IRB) and Ethics committee [IRB Min number 9227, dated 17.12.2014].

Sample size

DSPD has not been assessed using the PAID scale among the patients with T2DM from India. Hence, assuming a conservative estimate of a 50% prevalence of diabetes-related psychological distress with 7% precision, we had to screen 216 patients with T2DM.

Statistical analysis

The data were entered into EpiData software and analysed using Stata 13.1. The PAID score of ≥40 was considered to represent the presence of DSPD. The prevalence and 95% confidence intervals (CIs) of DSPD were estimated. A Chi-square test was used to find the association between binary or nominal socio-demographic, diabetes-related factors, complications and presence of DSPD and Chi-square test for trend for the ordinal factors. The strength of the association was expressed as odds ratio (OR). The relationship between BMI and DSPD was modelled using spline logistic regression and a test of difference in slopes was used to check the assumption of linearity.[16] Factors such as age, number of self-reported complications of T2DM, retinopathy and BMI which were significant at 0.20 level on univariate analysis were considered for multivariate analysis. Multiple logistic regression was used to find the independent effect of each factor on psychological distress. A final model was derived by including factors that were statistically significant at a level of 0.05. The Hosmer-Lemeshow's goodness-of-fit statistics (P > 0.05) was used to evaluate model fit.[17],[18] A receiver operating characteristic (ROC) curve was constructed by comparing the predicted probability of DSPD from the final model. A P value <0.05 was considered statistically significant.


  Results Top


A total of 253 questionnaires were completed: 154 in Tamil and 99 in English. The majority of the subjects were males (62.1%), aged 45–64 years (61.3%), from urban areas (64%) and married (88.1%). About one-third of subjects reported having been to college (34.8%). Nearly half of the study subjects (50.2%) had T2DM for more than 10 years [Table 1]. In all, 177 (70%) subjects reported one or more complications; neuropathy (42.7%) was the commonest, followed by foot problems (34.0%) [Table 2]. One or more additional illness other than T2DM was reported by 54.5% patients. Majority (51.4%) were on two anti-hyperglycaemic medications; generally, a very high level of adherence to medication (94.9%) was reported [Table 3].
Table 1: Characteristics of study population and their association with DSPD

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Table 2: Association of complications of T2DM with psychological distress

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Table 3: Self-reported comorbidities among T2DM

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Prevalence of DSPD

The median of the PAID score was 27.5 with an interquartile range (IQR) of 12.5 and 45.0. The prevalence of DSPD in this study was 32.8% (83/253) with a 95% CI of 27%–39%, suggesting that about one-third of the patients had a greater level of distress.

A feeling of distress about living with diabetes was not uncommon. All of the 20 items on the PAID scale were reported as a serious problem (score 4 on PAID) more than once [Figure 1]. 'Worrying about the future and possibility of serious complications' was the most frequently reported serious issue. 'Feeling scared, angry, depressed, overwhelmed and guilty, not having clear goals and not accepting diabetes' were also quoted as serious problems frequently. Alternatively, some issues were rarely perceived as distressing, such as 'feeling unsatisfied with your diabetes physician' and 'feeling that friends and family are unsupportive'.
Figure 1: Line graph showing the frequency in which the 20 PAID items were scored as a serious problem

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Impact of Socio-demographic and clinical factors on psychological distress

[Table 1], [Table 2], [Table 3] show the relationship of the baseline demographic and clinical factors to the PAID score.

A lower age (P = 0.023) and presence of diabetic retinopathy (P = 0.010) were found to have a statistically significant association with the PAID score in the univariate analysis. Body mass index (0.081), greater number of complications (P = 0.028), known nephropathy (P = 0.166), and having peripheral vascular disease (P = 0.108) were significantly associated with DSPD (on univariate analysis at 0.20 level). The relationship between BMI and DSPD was linear (P = 0.34) using a test for difference in slopes after a spline logistic regression.

Gender, employment, education, marital status and the duration of T2DM showed no significant association. Similarly, no significant association was found between the number of additional illnesses, diabetes medications, adherence to medications and the PAID score. However, it was observed that one-third of the sample within each of the factor groups had a high PAID score; for example, around 30% in each group of the 'duration of diabetes' had DSPD. Therefore, regardless of the socio-demographic or clinical factors about one-third of the sample was psychologically distressed.

From the multiple logistic regression, it was observed that the adjusted odds of having psychological distress was 3.65 (95% CI 1.36–9.80) times more for those aged between 25 and 44 years, and 2.53 (95% CI 1.23–5.21) times more for the age group of 45–64 years when compared with those older than 65 years. When self-reported complications were assessed, retinopathy had an OR of 2.60 (95% CI 1.12–6.04) for DSPD [Table 4]. For each unit increase in BMI, the odds of DSPD increase by 1.07 (95% CI 1.01–1.14). In the stepwise backward selection method, the P value for an overall effect of the number of complications on DSPD was 0.071 showing a trend towards increased distress in those with a greater number of complications of diabetes. Thus, age, retinopathy, number of complications and BMI were retained by the model. The Hosmer-Lemeshow goodness-of-fit statistics revealed that the model's prediction was similar to the observed (P = 0.61). The area under the curve of the ROC curve was 0.68 (95% CI 0.61–0.75).
Table 4: Multiple logistic regression of DSPD and socio-demographic and morbidity factors

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Acceptance of PAID questionnaire

The questionnaire was generally well accepted. More than 90% (228/253) found PAID easy to complete, and 84.6% (214/253) were willing to do it again. Also, the majority (83%) of subjects suggested that PAID was appropriate for the Indian population. The most confusing question was item number 20 – “Feeling 'burned out' by the constant efforts to manage diabetes” and this also was the question that most people were not happy to answer.


  Discussion Top


The purpose of this study was to establish the prevalence of DSPD among patients with T2DM using the PAID scale. The prevalence of DSPD in T2DM was 32.8%. Similar findings were reported from Malaysia and Germany (36% and 30.8%, respectively) with the PAID scale.[19],[20] A study from Southern India used Diabetes Distress Scale (DDS-17) and reported that diabetes distress is 27.9%.[21]

Anxiety regarding future complications was the most prominent distress, followed by emotional feelings related to diabetes such as feeling angry, depressed, guilty, overwhelmed, scared, concerns about low blood sugar levels or difficulty accepting their diabetes. Similar findings were also reported in previous studies.[8],[12],[19],[20],[22],[23] Identifying individual concerns helps physicians focus on those aspects while counselling patients, which would improve coping skills and diabetes self-management. Of interest, serious dissatisfaction with the diabetes physician was uncommon.

When we looked at the association of socio-demographic and clinical factors with the PAID score, only younger age and diabetic retinopathy showed significant association on univariate analysis. Other studies have also reported a higher level of DSPD among younger patients.[24],[25],[26],[27] Younger patients may perceive a chronic illness like diabetes as an obstacle to their life and cope less effectively than older adults.[25] Commitment to strict lifestyle changes and pharmacological regimens in T2DM may be particularly challenging for young patients with changing life circumstances, making them more prone to DSPD. In a cross-sectional study from Australia, Reddy et al. reported that the PAID score correlated positively with HbA1C.[23]

Self-reported diabetic retinopathy was associated with a 2.5-fold increased risk of DSPD in this study. A study by Polonsky et al. also reported a significantly higher PAID score with diabetic retinopathy.[8] Diabetic retinopathy is associated with marked psychological distress due to reduced functional ability, social isolation, and increased financial burden.[9],[28] Close attention to these high-risk groups is essential to reduce diabetes-related psychological distress and its negative influence on diabetes self-management and glycaemic control.

Furthermore, we observed that a greater number of complications of diabetes and higher BMI were associated with greater odds of developing DSPD. Obesity is a well-identified risk factor for psychological distress. Diabetes-related complications that included nephropathy and peripheral vascular disease also showed a greater association with DSPD compared to other comorbidities. However, neuropathy had a greater association with psychological distress in other published studies.[27] In our study, though neuropathy was the commonest complaint, it was not significantly associated with DSPD. Of interest, a larger proportion of studies on DSPD report a reciprocal link in which psychological distress leads to obesity and diabetes complications due to inactivity and poor glycaemic control.[29] The association could thus be interpreted as a vicious cycle, emphasising the need to identify factors contributing to psychological distress in individual patients, and suggesting coping strategies.

Female gender, lower educational status, being single, longer duration of diabetes, smoking and alcohol consumption, and low income have been reported to be associated with the increased risk of depression and psychological distress in diabetes.[7],[27],[28],[30] Our study did not show any significant association between these factors and DSPD. Nevertheless, an interesting observation was that regardless of socio-demographic and clinical factors, one-third of the subjects in all groups had DSPD (PAID score ≥40). Consequently, it is necessary to screen all patients with diabetes for DSPD, and not only the perceived high-risk groups. The majority of the patients with T2DM are managed by primary care physicians. Assessment for DSPD using the PAID scale can lead to individualized diabetes education addressing the identified barriers and needs of different patients. Various studies have reinforced that diabetes self-management education and continued support improves diabetes outcomes.[31],[32]

Finally, this study has shown that it is possible to measure DSPD in a busy clinical setting using PAID. The acceptability of the questionnaire was demonstrated by the high participation, very few declining to participate, and the willingness of patients to complete it again. PAID has been quoted by NICE and ADA guidelines for the assessment of psychological distress in diabetes.[7] Diabetes management plans should incorporate both glycaemic control and psychological well-being.[33] This preliminary data suggests that PAID is a valuable screening tool for DSPD, and may thus facilitate counselling on the specific concerns of patients to help them cope better with their diabetes.

The study is not without limitations. Firstly, the cross-sectional nature limits the ability to interpret the causal factors. Secondly, the socio-demographic and clinical data were self-reported by the patients. The reliability of some findings can be debated, especially the high level of medication adherence. In addition, although the Tamil questionnaire was translated by two independent bi-lingual individuals, a study to validate the questionnaire statistically would have been better.

Further longitudinal studies are required to understand the effect of interventions to address the individual concerns expressed by the patients in the PAID questionnaire, on coping abilities, long-term glycaemic control and complications of diabetes.


  Conclusions Top


This cross-sectional study showed that one-third of the T2DM patients had DSPD. The prevalence was significantly higher in younger individuals and in those with retinopathy. It was also noted that one-third of the patients were likely to be psychologically distressed regardless of their socio-demographic or clinical characteristics. Hence, to ensure good adherence to diabetic care plans, it is necessary to screen all the patients with T2DM for psychological well-being. PAID is an easy, well-accepted questionnaire by the patients. It may help in identifying psychosocial barriers affecting diabetes management, which need to be addressed to improve outcomes. We recommend linking psychological screening into the guidelines of diabetes care for better outcomes of patients with diabetes.

Key points

  • About one-third of the patients with T2DM have DSPD.
  • Younger age and diabetic retinopathy were significant risk factors associated with increased psychological distress. Worrying about future complications was the most commonly reported problem.
  • The PAID scale is a well-accepted, easy-to-use tool for the assessment of DSPD in Indian patients.
  • Future studies are needed to assess the impact of individualized patient education based on the problem areas identified, on their QoL and long-term clinical outcomes.


New message

Though rarely assessed, DSPD is a significant problem affecting one-third of the patients with T2DM. The PAID scale is an acceptable and easy-to-use tool for the evaluation of DSPD in Indian patients.

Declaration of patient consent

The authors certify that they have obtained all appropriate patient consent forms. In the form, the patients have given consent for their clinical information to be reported in the journal

Acknowledgement

This study was undertaken as a part of a student elective project by the first author. It was mainly self-funded but was also supported by the 'Friends of Vellore' bursary. Special thanks to Dr Kirsty MacLennan, Clinical psychologist at Aberdeen Royal Infirmary for the assistance with project planning and the staff at Christian Medical College, Vellore for general support.

Financial support and sponsorship

Nil.

Conflicts of interest

There are no conflicts of interest.

 
  References Top

1.
Mohan V, Sandeep S, Deepa R, Shah B, Varghese C. Epidemiology of type 2 diabetes: Indian scenario. Indian J Med Res 2007;125:217-30.  Back to cited text no. 1
[PUBMED]  [Full text]  
2.
Wild S, Roglic G, Green A, Sicree R, King H. Global prevalence of diabetes: Estimates for the year 2000 and projections for 2030. Diabetes Care 2004;27:1047-53.  Back to cited text no. 2
    
3.
India State-Level Disease Burden Initiative Diabetes Collaborators. The increasing burden of diabetes and variations among the states of India: the Global Burden of Disease Study 1990-2016. Lancet Glob Health 2018;6: e1352-e1362. doi: 10.1016/S2214-109X(18)30387-5.  Back to cited text no. 3
    
4.
Gupta R, Misra A. Review: Type 2 diabetes in India: Regional disparities. Br J Diabetes Vasc Dis 2007;7:12-6.  Back to cited text no. 4
    
5.
Deepa M, Pradeepa R, Rema M, Mohan A, Deepa R, Shanthirani S, et al. The Chennai Urban Rural EpidemiologyStudy (CURES)-study design and methodology (urbancomponent) (CURES-I). J Assoc Physicians India 2003;51: 863-70.  Back to cited text no. 5
    
6.
Virtanen M, Ferrie JE, Tabak AG, Akbaraly TN, Vahtera J, Singh-Manoux A, et al. Psychological distress and incidence of type 2 diabetes in high-risk and low-risk populations: The Whitehall II Cohort Study. Diabetes Care 2014;37:2091-7.  Back to cited text no. 6
    
7.
Kalra S, Sridhar GR, Balhara YP, Sahay RK, Bantwal G, Baruah MP, et al. National recommendations: Psychosocial management of diabetes in India. Indian J Endocrinol Metab 2013;17:376-95.  Back to cited text no. 7
    
8.
Polonsky WH, Anderson BJ, Lohrer PA, Welch G, Jacobson AM, Aponte JE, et al. Assessment of diabetes-related distress. Diabetes Care 1995;18:754-60.  Back to cited text no. 8
    
9.
Lloyd CE, Pouwer F, Hermanns N, editors. Screening for Depression and Other Psychological Problems in Diabetes: A Practical Guide. London: Springer-Verlag; 2013.  Back to cited text no. 9
    
10.
Polonsky WH. Understanding and assessing diabetes-specific quality of life. Diabetes Spectr 2000;13:36.  Back to cited text no. 10
    
11.
Sridhar GR. Psychiatric co-morbidity & diabetes. Indian J Med Res 2007;125:311-20.  Back to cited text no. 11
[PUBMED]  [Full text]  
12.
Welch GW, Jacobson AM, Polonsky WH. The Problem Areas in Diabetes scale. An evaluation of its clinical utility. Diabetes Care 1997;20:760-6.  Back to cited text no. 12
    
13.
Lee EH, Lee YW, Lee KW, Kim YS, Nam MS. Measurement of diabetes-related emotional distress using the Problem Areas in Diabetes scale: Psychometric evaluations show that the short form is better than the full form. Health Qual Life Outcomes 2014;12:142.  Back to cited text no. 13
    
14.
Welch G, Weinger K, Anderson B, Polonsky WH. Responsiveness of the Problem Areas in Diabetes (PAID) questionnaire. Diabet Med 2003;20:69-72.  Back to cited text no. 14
    
15.
Snoek FJ, Pouwer F, Welch GW, Polonsky WH. Diabetes-related emotional distress in Dutch and U.S. diabetic patients: Cross-cultural validity of the problem areas in diabetes scale. Diabetes Care 2000;23:1305-9.  Back to cited text no. 15
    
16.
Greenland S. Dose-response and trend analysis in epidemiology: Alternative to categorical analysis. Epidemiology 1995;6:356-65.  Back to cited text no. 16
    
17.
Hosmer DW, Hosmer T, Le Cessie S, Lemeshow S. A comparison of goodness-of-fit tests for the logistic regression model. Stat Med 1997;16:965-80.  Back to cited text no. 17
    
18.
Pulkstenis E, Robinson TJ. Two goodness-of-fit tests for logistic regression models with continuous covariates. Stat Med 2002;21:79-93.  Back to cited text no. 18
    
19.
Jannoo Z, Yap B, Razali N, Gnanasan S, Hassali M, Shafie A, et al. Examining the Problem Areas In Diabetes scale (MY-PAID-20) among Malay T2DM patients. Int J Bio and Biomed Engineering 2014;8:157-63.  Back to cited text no. 19
    
20.
Hermanns N, Kulzer B, Krichbaum M, Kubiak T, Haak T. How to screen for depression and emotional problems in patients with diabetes: Comparison of screening characteristics of depression questionnaires, measurement of diabetes-specific emotional problems and standard clinical assessment. Diabetologia 2006;49:469-77.  Back to cited text no. 20
    
21.
Sankar P, Sasikumar P, Medayil R, Jacob R, Sasidharan S. High prevalence of distress among patients with Type 2 diabetes (T2DM)—A hospital-based, cross-sectional study from South India. Diabetes 2018;67(Supplement 1):61-LB. doi: 10.2337/db18-61-LB.  Back to cited text no. 21
    
22.
Amsberg S, Wredling R, Lins P, Adamson U, Johansson U. The psychometric properties of the Swedish version of the Problem Areas in Diabetes Scale (Swe-PAID-20): Scale development. Int J Nurs Stud 2008;45:1319-28.  Back to cited text no. 22
    
23.
Reddy J, Wilhelm K, Campbell L. Putting PAID to diabetes-related distress: The potential utility of the problem areas in diabetes (PAID) scale in patients with diabetes. Psychosomatics 2013;54:44-51.  Back to cited text no. 23
    
24.
Fisher L, Mullan JT, Skaff MM, Glasgow RE, Arean P, Hessler D. Predixtingdiabetes distress in patients with Type 2 diabetes: A longitudinal study. Diabet Med 2009;26:622-7.  Back to cited text no. 24
    
25.
Baradaran HR, Mirghorbani S, Javanbakht A, Yadollahi Z, Khamseh ME. Diabetes distress and its association with depression in patients with type 2 diabetes in Iran. Int J Prev Med 2013;4:580-4.  Back to cited text no. 25
    
26.
Delahanty LM, Grant RW, Wittenberg E, Bosch JL, Wexler DJ, Cagliero E, et al. Association of diabetes-related emotional distress with diabetes treatment in primary care patients with Type 2 diabetes. Diabet Med 2007;24:48-54.  Back to cited text no. 26
    
27.
Stoop CH, Nefs G, Pop VJ, Wijnands-van Gent CJ, Tack CJ, Geelhoed-Duijvestijn PH, et al. Diabetes-specific emotional distress in people with Type 2 diabetes: A comparison between primary and secondary care. Diabet Med 2014;31:1252-9.  Back to cited text no. 27
    
28.
Fenwick E, Rees G, Pesudovs K, Dirani M, Kawasaki R, Wong TY, et al. Social and emotional impact of diabetic retinopathy: A review. ClinExpOphthalmol 2012;40:27-38.  Back to cited text no. 28
    
29.
Huyser KR, Manson SM, Nelson LA; Noonan C, Roubideaux Y; Special Diabetes Program; Indians Healthy Heart Demonstration Project.Serious psychological distress and diabetes management among American Indians and Alaska Natives. Ethn Dis 2015;25:145-51.  Back to cited text no. 29
    
30.
Collins MM, Corcoran P, Perry IJ. Anxiety and depression symptoms in patients with diabetes. Diabet Med 2009;26:153-61.  Back to cited text no. 30
    
31.
Parildar H, Cigerli O, Demirag NG. Depression, coping strategies, glycaemic control and patient compliance in Type 2 diabetic patients in an endocrine outpatient clinic. Pak J Med Sci 2015;31:19-24.  Back to cited text no. 31
    
32.
Hopkins D, Lawrence I, Mansell P, Thompson G, Amiel S, Campbell M, et al. Improved biomedical and psychological outcomes 1 year after structured education in flexible insulin therapy for people with type 1 diabetes: The U.K. DAFNE experience. Diabetes Care 2012;35:1638-42.  Back to cited text no. 32
    
33.
Miller ST, Elasy TA. Psychometric evaluation of the Problem Areas in Diabetes (PAID) survey in Southern, rural African American women with Type 2 diabetes. BMC Public Health 2008;22:70.  Back to cited text no. 33
    


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