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Year : 2019  |  Volume : 8  |  Issue : 7  |  Page : 2173-2178

Management of radiation-induced proctitis

1 Department of Radiation Oncology, Sabzevar University of Medical Sciences, Kermanshah, Iran
2 Department of Radiation Oncology, Imam Reza Hospital of Kermanshah, Kermanshah, Iran

Correspondence Address:
Dr. Malihe Dayani
Department of Radiation Oncology, Imam Reza Hospital of Kermanshah, Kermanshah
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jfmpc.jfmpc_333_19

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The occurrence of chronic proctitis as a side effect among radiotherapy patients is about 5%. Radiation proctitis and consequent development of chronic proctitis are not associated to each other. However, a lot of samples of proctitis that are limited easily could be treated by typical remedial techniques. Improvements in radiotherapy techniques that make possible the delivery of superior doses of radiation could easily reduce both chronic and acute proctitis. The step-by-step remedial procedure for treatment of this disorder starts with conservative remedial management and includes iron substitution as a second-line therapy. For patients who did not receive initial therapies, sucralfate injection, topical corticosteroids, and antidiarrhea therapy were provided as a means of aggressive care. In cases of continuous rectal bleeding, remedial laser techniques and formaldehyde administration should be attempted before surgical therapy. When surgical therapy is required, a descending or transverse colostomy must be carried out. Advanced methods such as intraperitoneal injections of formalin or novel methods of cold therapy and radiofrequency ablation (RFA) provide a wider remedial field. Exceptionally, unanticipated conclusion of neosquamous wound healing via RFA may have additional preponderances in stopping symptoms and may require better assessment through accurate randomized examination. Since aggressive treatments like coloanal anastomosis and colorectal surgery are correlated with remarkable mortality and morbidity, they must be considered as the final course of remedial treatment.

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