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Year : 2019  |  Volume : 8  |  Issue : 4  |  Page : 1504-1507

Hemophagocytic lymphohistiocytosis as a diagnostic consideration of fever of unknown origin with pancytopenia and chronic liver disease

1 Department of Medicine, All India Institute of Medical Sciences (AIIMS), Rishikesh, Uttarakhand, India
2 Department of Paediatrics, Government Doon Medical College, Dehradun, Uttarakhand, India

Correspondence Address:
Dr. Vyas K Rathaur
House No. 405, Stuti, Swarn Ganga Residency, Near Veerbhadra Mandir, Rishikesh, Uttarakhand - 249 201
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jfmpc.jfmpc_190_19

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Hemophagocytic lymphohistiocytosis (HLH) is a severe disorder of systemic immune dysregulation which can be primary or secondary to autoimmune disorders, malignancy, or infections. We hereby describe a case of a 23-year-old male with severe hepatitis along with pancytopenia and prolonged fever of unknown origin that developed HLH triggered by staphylococcal urinary tract infection. This is a discussion of this unusual disease and its presentation and the diagnostic difficulties which may be encountered in general clinical practice.

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